21 Dec Semaglutide and Ozempic: What’s the difference?
Semaglutide and Ozempic are two medications that have gained popularity for their ability to promote weight loss. Both drugs belong to a class of medications called GLP-1 receptor agonists, and they have been approved by the U.S. Food and Drug Administration (FDA) for the treatment of obesity. While both semaglutide and Ozempic are effective at helping individuals lose weight, there are some differences between the two medications that are worth considering. Continue reading to learn more from Island Rheumatology!
Mechanism of Action:
Semaglutide is a once-daily injectable medication that works by mimicking the action of a hormone called GLP-1 (glucagon-like peptide-1). GLP-1 is released naturally by the gut and stimulates insulin release, lowers blood sugar levels, and reduces appetite. By activating the GLP-1 receptor, semaglutide helps to regulate blood sugar levels and decrease the feeling of hunger, ultimately leading to weight loss. Ozempic, on the other hand, is also a GLP-1 receptor agonist that works in a similar manner to semaglutide. It helps to lower blood sugar levels, slow down gastric emptying, and reduce appetite. However, Ozempic is administered once weekly, making it a more convenient option for some individuals.
Dosage and Administration – How Island Rheumatology Helps:
Semaglutide is available in three different doses: 0.5 mg, 1 mg, and 2.4 mg. The typical starting dose is 0.25 mg once weekly for four weeks, followed by an increase to 0.5 mg once weekly. If further weight loss is desired, the dose can be increased to 1 mg once weekly. Semaglutide is self-administered as a subcutaneous injection in the abdomen, thigh, or upper arm. Ozempic, on the other hand, comes in a single dose of 0.25 mg or 0.5 mg, and the starting dose is usually 0.25 mg once weekly for four weeks, followed by an increase to 0.5 mg once weekly. Ozempic is also self-administered as a subcutaneous injection, typically in the abdomen.
Efficacy:
Both semaglutide and Ozempic have shown significant efficacy in promoting weight loss. In one clinical trial called the Semaglutide Treatment Effect in People with Obesity (STEP) trial, it was found that individuals who took semaglutide lost an average of 15% of their body weight over 68 weeks. This was significantly more than the placebo group, which only lost an average of 2.4% of their body weight. Similarly, in the SUSTAIN 7 trial, Ozempic was found to promote weight loss. Participants in the trial who took Ozempic lost an average of 9.4% of their body weight, compared to only 3.4% in the placebo group.
Side Effects:
Both semaglutide and Ozempic may cause similar side effects, including nausea, vomiting, diarrhea, constipation, stomach pain, and decreased appetite. However, these side effects are usually mild to moderate and diminish over time as the body adjusts to the medication. It is important to note that everyone’s experience with medications can vary, and some individuals may experience side effects to a greater or lesser degree.
Cost:
The cost of both semaglutide and Ozempic can vary depending on insurance coverage and pharmacy discounts. However, Ozempic tends to be slightly more affordable than semaglutide. It is always advisable to check with your insurance provider or pharmacist to determine the cost of these medications.
Contact Island Rheumatology and Osteoporosis, PC. Today!
Semaglutide and Ozempic are both effective medications for weight loss. They belong to the same class of drugs, have similar mechanisms of action, and are self-administered as subcutaneous injections. While semaglutide is available in three different doses and is administered once daily, Ozempic is only available in two doses and is administered once weekly. Ultimately, the choice between semaglutide and Ozempic should be made in consultation with a healthcare provider, taking into account factors such as individual preferences, cost, and potential side effects. Both medications have shown significant efficacy in promoting weight loss, and with the right support and lifestyle changes, they can be effective tools in managing obesity and improving overall health.
Please note that the information provided in this article is for informational purposes only and should not be used as a substitute for professional medical advice or treatment. Always consult with a healthcare professional before starting any new medication or weight loss program.
If you would like an appointment to discuss weight loss options please request an appointment below, email us at support@islandrheumatology.com or call 631-886-2844 option 3.